Differentiation between two ligands for peripheral benzodiazepine binding sites, [3H]R05-4864 and [3H]PK 11195, by thermodynamic studies

Agonist and antagonist benzodiazepine receptor interaction in vitro

H. Möhler, J. G. Richards · Nature · 1981 · 381 citations

Molecular Pharmacology, Functional Selectivity, Medicine +5

Peripheral benzodiazepine binding sites: Effect of PK 11195, 1-(2-chlorophenyl)-n-methyl-n-(1-methylpropyl)-3-isoquinolinecarboxamide

G. Le Fur, M.L. Perrier, Nadine Vaucher et al. · Life Sciences · 1983 · 341 citations

Medicinal Chemistry, Medicine, Peripheral Benzodiazepine +5

Fundamental difference between the molecular interactions of agonists and antagonists with the β-adrenergic receptor

Gregory A. Weiland, Kenneth P. Minneman, Perry B. Molinoff · Nature · 1979 · 258 citations

Molecular Pharmacology, Molecular Interactions, Fundamental Difference +9

Specific high-affinity saturable binding of [3H] Ro5-4864 To benzodiazepine binding sites in the rat cerebral cortex

Hans E. Schoemaker, Marla Bliss, Henry I. Yamamura · European Journal of Pharmacology · 1981 · 239 citations

Neurophysiology, Neuroanatomy, Medicine +9

Peripheral benzodiazepine binding sites: Effect of PK 11195, 1-(2-chlorophenyl)-n-methyl-(1-methylpropyl)-3 isoquinolinecarboxamide

G. Le Fur, F. Guilloux, Pierre Rufat et al. · Life Sciences · 1983 · 227 citations

Medicinal Chemistry, Medicine, Peripheral Benzodiazepine +6