Concepedia

Role of CYP3A and CYP2E1 in Alcohol-Mediated Increases in Acetaminophen Hepatotoxicity: Comparison of Wild-Type and Cyp2e1(–/–) Mice

Kristina Wolf, Sheryl G. Wood, Jenna L. Allard, Jane A. Hunt, Nadia Gorman, Brooke W. Walton-Strong, Juliana G. Szakacs, Su Duan, Qin Hao, Michael H. Court,

Drug Metabolism and Disposition · 2007 · 59 citations · 49 references

DOI

Concepts

References

49

ACETAMINOPHEN-INDUCED HEPATIC NECROSIS. IV. PROTECTIVE ROLE OF GLUTATHIONE

J.R. Mitchell, David J. Jollow, William Z. Potter et al. · Journal of Pharmacology and Experimental Therapeutics · 1973 · 1.7K citations

, , +17

Acetaminophen-Induced Hepatic Necrosis

David J. Jollow, S S Thorgeirsson, William Z. Potter et al. · Pharmacology · 2008 · 1.1K citations

, , +17

Role of CYP2E1 in the Hepatotoxicity of Acetaminophen

Susanna S.T. Lee, Jeroen Buters, Thierry Pineau et al. · Journal of Biological Chemistry · 1996 · 658 citations · Full text

, , +15

Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.

Deborah J. Newton, R W Wang, Anthony Y.H. Lu · Drug Metabolism and Disposition · 1995 · 606 citations

, , +17

Purification and characterization of a unique isozyme of cytochrome P-450 from liver microsomes of ethanol-treated rabbits.

Dennis R. Koop, Edward T. Morgan, George E. Tarr et al. · Journal of Biological Chemistry · 1982 · 537 citations · Full text

, , +13