American Journal of Tropical Medicine and Hygiene · 2006 · 43 citations · 40 references
Veterinary MedicineAnimal SciencesInfectious DiseasesOutbreak InvestigationVirologyZoonotic Disease EpidemiologyAnimal Infectious DiseasesLivestock Infectious DiseasesLivestock-associated ZoonosesSwine EpidemiologySwine Infectious DiseasesViral HepatitisEpidemiology In LivestockHepatitis E Virus InfectionHepatitis SerologyLivestock Disease RiskLivestock Viral DiseasesMeat-borne InfectionsMeat-borne PathogensPathogen Shedding In Livestock
Zoonotic infections caused by eating the meat of deer, wild boar, and pig have been suggested in Japan, a country that is not epidemic for hepatitis E caused by hepatitis E virus (HEV). This virus is widely spread in domestic pigs in both epidemic and non-epidemic countries. We studied fecal HEV shedding patterns on three Japanese farms that had two common genotype III HEV strains. Two of the three farms had high shedding peaks (75% and 100%) in pigs 1-3 months of age, suggesting that these animals had the highest risk of spreading HEV through feces. Another farm had a low shedding rate in animals six months of age and a low prevalence of the IgG antibody to HEV. Fecal IgA antibody to HEV was found in sucking pigs < 13 days of age on farms that had high and low shedding patterns. A small fraction of pigs (3 of 43 [7%]) at the finishing stage (5-6 months of age) still shed HEV on the three farms.
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Julie Thompson, Desmond G. Higgins, Toby J. Gibson · Nucleic Acids Research · 1994 · 64.9K citations · Full text
Yasuyuki Yazaki, Hitoshi Mizuo, Masaharu Takahashi et al. · Journal of General Virology · 2003 · 599 citations