The gene encoding the prostatic tumor suppressor PSP94 is a target for repression by the Polycomb group protein EZH2

The polycomb group protein EZH2 is involved in progression of prostate cancer

Sooryanarayana Varambally, Saravana M. Dhanasekaran, Ming Zhou et al. · Nature · 2002 · 2.7K citations · Full text

Tumor Biology, Chromatin, Chromatin Structure +8

The Polycomb group protein EZH2 directly controls DNA methylation

Emmanuelle Viré, Carmen Brenner, Rachel Deplus et al. · Nature · 2005 · 2.2K citations

Chromatin, Epigenetic Change, Genetics +7

Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions

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Histone Modifications, Epigenetic Change, Genetics +20

EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer

Adrian P. Bracken · The EMBO Journal · 2003 · 1.2K citations · Full text

Tumor Biology, Oncology, Medicine +10

Increased Expression of Genes Converting Adrenal Androgens to Testosterone in Androgen-Independent Prostate Cancer

Michael Stanbrough, Glenn J. Bubley, Kenneth N. Ross et al. · Cancer Research · 2006 · 1.1K citations · Full text