Enzymes involved in the biosynthesis of leukotriene B4 and prostaglandin E2 are active in sebaceous glands

Leukotrienes: Mediators of Immediate Hypersensitivity Reactions and Inflammation

Bengt Samuelsson · Science · 1983 · 2.9K citations

Life Sciences, Immunology, Pharmacology +14

Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors α and γ

Steven A. Kliewer, Scott S. Sundseth, Stacey A. Jones et al. · Proceedings of the National Academy of Sciences · 1997 · 2.2K citations · Full text

Life Sciences, Molecular Biology, Pharmacology +16

A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation

Steven A. Kliewer, James M. Lenhard, Timothy M. Willson et al. · Cell · 1995 · 2K citations · Full text

Life Sciences, Biochemistry, Physiology +16

The PPARα–leukotriene B4 pathway to inflammation control

Pallavi R. Devchand, H. J. Keller, Jeffrey M. Peters et al. · Nature · 1996 · 1.4K citations

Life Sciences, Molecular Biology, Pharmacology +12

Peroxisome Proliferator-activated Receptor α Negatively Regulates the Vascular Inflammatory Gene Response by Negative Cross-talk with Transcription Factors NF-κB and AP-1

Philippe Delerive, Karolien De Bosscher, Sandrine Besnard et al. · Journal of Biological Chemistry · 1999 · 1.1K citations · Full text

Life Sciences, Cell Biology, Physiology +17