Concepedia

Novel insights into osteogenesis and matrix remodelling associated with calcific uraemic arteriolopathy

Rafael Kramann, Vincent Brandenburg, Leon J. Schurgers, Markus Ketteler, Saskia Westphal, Isabelle Leisten, Manfred Bovi, Willi Jahnen‐Dechent, Ruth Knüchel, Jürgen Floege,

Nephrology Dialysis Transplantation · 2012 · 96 citations · 40 references

DOIFull text

Open access

Abstract

Our data indicate that CUA is an active osteogenic process including the upregulation of BMP-2 signalling, hydroxyapatite deposition and extensive matrix remodelling of the subcutis.

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