Concepedia

Characterization of a Molecular Chaperone Present in the Eukaryotic Flagellum

Jessica Shapiro, Jessica R. Ingram, Karl A. Johnson

Eukaryotic Cell · 2005 · 15 citations · 25 references

DOIFull text

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Concepts

Abstract

Chlamydomonas flagella contain a molecular chaperone now identified as HSP70A, a major cytoplasmic isoform. HSP70A synthesis is upregulated by deflagellation, and its distribution in the flagellum overlaps with the IFT kinesin-II motor FLA10. HSP70A may chaperone flagellar proteins during transport, participating in the assembly and maintenance of the flagellum.

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