Concepedia

Expression profile of the small heat-shock protein alpha-B-crystallin in operated-on non-small-cell lung cancer patients: clinical implication☆☆☆

Radostina Cherneva, Danail Petrov, Ognian Georgiev, Yanina Slavova, Maria Stamenova, N. Trifonova

European Journal of Cardio-Thoracic Surgery · 2009 · 14 citations · 16 references

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Abstract

Alpha-B-crystallin plays an essential role in NSCLC biology and its nuclear staining is an independent factor of poor survival. Its clinical application in molecular biologic substaging of NSCLC patients needs further validation.

References

16

The Small Heat Shock Protein αB-Crystallin Negatively Regulates Cytochrome c- and Caspase-8-dependent Activation of Caspase-3 by Inhibiting Its Autoproteolytic Maturation

Merideth C. Kamradt, Feng Chen, Vincent L. Cryns · Journal of Biological Chemistry · 2001 · 352 citations · Full text

Phosphorylation-Dependent Ubiquitination of Cyclin D1 by the SCFFBX4-αB Crystallin Complex

Douglas I. Lin, Olena Barbash, Suresh Kumar et al. · Molecular Cell · 2006 · 341 citations · Full text

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Human αA- and αB-crystallins bind to Bax and Bcl-XS to sequester their translocation during staurosporine-induced apoptosis

Yingwei Mao, JP Liu, Hua Xiang et al. · Cell Death and Differentiation · 2004 · 326 citations · Full text

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The Small Heat Shock Protein αB-crystallin Is a Novel Inhibitor of TRAIL-induced Apoptosis That Suppresses the Activation of Caspase-3

Merideth C. Kamradt, Meiling Lü, Michael E. Werner et al. · Journal of Biological Chemistry · 2005 · 211 citations · Full text

Proteomics of buccal squamous cell carcinoma: The involvement of multiple pathways in tumorigenesis

Jia Chen, Qing‐Yu He, Anthony P.W. Yuen et al. · PROTEOMICS · 2004 · 128 citations