In cardiac myocytes, cAMP elevation triggers the down-regulation of transcripts and promoter activity for cyclic AMP phosphodiesterase-4A10 (PDE4A10)

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

Julie Thompson, Desmond G. Higgins, Toby J. Gibson · Nucleic Acids Research · 1994 · 64.9K citations · Full text

Life Sciences, Bioinformatics, Sequence Analysis +14

Discrete Microdomains with High Concentration of cAMP in Stimulated Rat Neonatal Cardiac Myocytes

Manuela Zaccolo, Tullio Pozzan · Science · 2002 · 843 citations

Life Sciences, Biochemistry, Cell Biology +14

A novel Epac-specific cAMP analogue demonstrates independent regulation of Rap1 and ERK

Jorrit M. Enserink, Anne Elisabeth Christensen, Johan de Rooij et al. · Nature Cell Biology · 2002 · 696 citations

Life Sciences, Cell Biology, Molecular Biology +10

Inducibility and negative autoregulation of CREM: An alternative promoter directs the expression of ICER, an early response repressor

Carlos A. Molina, Nicholas S. Foulkes, Enzo Lalli et al. · Cell · 1993 · 603 citations

Life Sciences, Molecular Biology, Molecular Genetics +13

Phosphorylation and Activation of a cAMP-specific Phosphodiesterase by the cAMP-dependent Protein Kinase

Claudio Sette, Marco Conti · Journal of Biological Chemistry · 1996 · 409 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13