Expression of E-cadherin and vimentin correlates with metastasis formation in head and neck squamous cell carcinoma patients

Impact of epidermal growth factor receptor expression on survival and pattern of relapse in patients with advanced head and neck carcinoma.

K. Kian Ang, Brian Berkey, Xiaoyu Tu et al. · PubMed · 2002 · 1.2K citations

Medicine, Oncology, Carcinogenesis +13

The protein kinase Akt induces epithelial mesenchymal transition and promotes enhanced motility and invasiveness of squamous cell carcinoma lines.

Sylvia Grille, Alfonso Bellacosa, John J. Upson et al. · PubMed · 2003 · 617 citations

Medicine, Cell Biology, Oncology +17

Distinct roles of Akt1 and Akt2 in regulating cell migration and epithelial–mesenchymal transition

Hanna Y. Irie, Rachel V. Pearline, Dorre A. Grueneberg et al. · The Journal of Cell Biology · 2005 · 590 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

E‐cadherin‐mediated adhesion inhibits ligand‐dependent activation of diverse receptor tyrosine kinases

Xiaolan Qian, Tatiana Karpova, Allan Sheppard et al. · The EMBO Journal · 2004 · 396 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Differential roles of ERK and Akt pathways in regulation of EGFR-mediated signaling and motility in prostate cancer cells

Yan Gan, Chengjian Shi, Landon J. Inge et al. · Oncogene · 2010 · 269 citations

Medicine, Molecular Biology, Oncology +17