REDUCTION OF ENDOTHELIAL AND SMOOTH MUSCLE DENSITY IN THE CORPORA CAVERNOSA OF THE STREPTOZOTOCIN INDUCED DIABETIC RAT

Tatjana Burchardt, Martin Burchardt, J. KARDEN, Ralph Buttyan, Ahmad Shabsigh, Alexandre de la Taille, Pui Yee Ng, A. G. ANASTASIADIS, Ridwan Shabsigh

The Journal of Urology · 2000 · 83 citations · 40 references

Abstract

Using the streptozotocin treated rat as a model for diabetes, we showed that smooth muscle and endothelial cell density is significantly decreased in diabetic corpora cavernosa but not in normal aged rats. This observation is a further step toward the understanding of the pathomechanisms for diabetic related erectile dysfunction.

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