An essential role for membrane rafts in the initiation of Fas/CD95‐triggered cell death in mouse thymocytes

Functional rafts in cell membranes

Kai Simons, Elina Ikonen · Nature · 1997 · 9.7K citations

Life Sciences, Biochemistry, Cell Biology +14

FLICE, A Novel FADD-Homologous ICE/CED-3–like Protease, Is Recruited to the CD95 (Fas/APO-1) Death-Inducing Signaling Complex

Marta Muzio, Arul M. Chinnaiyan, Frank Kischkel et al. · Cell · 1996 · 3.1K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

Regulation of Renal Organic Anion Transporter 3 (SLC22A8) Expression and Function by the Integrity of Lipid Raft Domains and their Associated Cytoskeleton

Chutima Srimaroeng, Jennifer Perry Cecile, Ramsey Walden et al. · Cellular Physiology and Biochemistry · 2013 · 3K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

FADD, a novel death domain-containing protein, interacts with the death domain of fas and initiates apoptosis

Arul M. Chinnaiyan, Karen O’Rourke, Muneesh Tewari et al. · Cell · 1995 · 2.4K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

Cytotoxicity‐dependent APO‐1 (Fas/CD95)‐associated proteins form a death‐inducing signaling complex (DISC) with the receptor.

Frank Kischkel, Stefan Hellbardt, Iris Behrmann et al. · The EMBO Journal · 1995 · 2.1K citations · Full text

Life Sciences, Cell Biology, Immunology +13