Increased Rho-Kinase Activity in Hypertensive Patients With Left Ventricular Hypertrophy

Abstract

ROCK activity is higher in hypertensive patients with LVH compared with hypertensive patients without LVH, and it is further increased when eccentric LVH is present. Thus, in hypertension, ROCK activation is related to pathological cardiac remodeling and might have a role as an LVH marker.