Catecholamine Release–Inhibitory Peptide Catestatin (Chromogranin A _352–372 )

Abstract

The catestatin Gly364Ser variant causes profound changes in human autonomic activity, both parasympathetic and sympathetic, and seems to reduce risk of developing hypertension, especially in men. A model for catestatin action in the baroreceptor center of the nucleus of the tractus solitarius accounts for these actions.