Angiotensin‐(1–7) induces cerebral ischaemic tolerance by promoting brain angiogenesis in a <scp>M</scp>as/<scp>eNOS</scp>‐dependent pathway

Abstract

This is the first evidence that Ang-(1-7) promotes brain angiogenesis via a Mas/eNOS-dependent pathway, which enhances tolerance against subsequent cerebral ischaemia. These findings highlight brain Ang-(1-7)/Mas signalling as a potential target in stroke prevention.