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Assessment of Differential Blockade by Amitriptyline and Its N -Methyl Derivative in Different Species by Different Routes

DOIFull Paper Access

53

Citations

7

References

2003

Year

Peter Gerner, Anna E. Haderer, Mustafa G. Mujtaba, Yukari Sudoh, Sanjeet Narang, Salahadin Abdi, V Srinivasa, Christof Pertl, Ging Kuo Wang
Anesthesiology

Abstract

Amitriptyline and N-methyl amitriptyline are potent Na+ channel blockers and show greater differential blockade in sheep than in rats. This differential blockade in sheep is greater than that produced by lidocaine or bupivacaine.

References

YearCitations

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