Human papillomavirus as a risk factor in oral carcinogenesis: a study using <i>in situ</i> hybridization with signal amplification

Abstract

The results suggest that HPV is not likely to play a role in the progression of malignant transformation in oral lesions. Nevertheless, the increased prevalence of HPV infection compared to normal oral mucosa and the fact that high-risk HPV types were the most frequently identified do not allow the exclusion of HPV as a risk factor in oral carcinogenesis.