Concepedia

Publication | Open Access

Cabozantinib Overcomes Crizotinib Resistance in ROS1 Fusion–Positive Cancer

DOIFull Paper Access

198

Citations

22

References

2014

Year

Ryohei Katayama, Yuka Kobayashi, Luc Friboulet, Elizabeth L. Lockerman, Sumie Koike, Alice T. Shaw, Jeffrey A. Engelman, Naoya Fujita
Clinical Cancer Research

Abstract

We developed a comprehensive model of acquired resistance to ROS1 inhibitors in NSCLC with ROS1 rearrangement and identified cabozantinib as a therapeutic strategy to overcome the resistance.

References

YearCitations

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