Giant Amphiphiles by Cofactor Reconstitution

Mark J. Boerakker, Jurry M. Hannink, Paul H. H. Bomans, Peter M. Frederik, Roeland J. M. Nolte, Emmo M. Meijer, Nico A. J. M. Sommerdijk

Angewandte Chemie International Edition · 2002 · 144 citations · 0 references

Concepts

Abstract

Controlled modification of horseradish peroxidase with an apolar polymer chain (see figure) by cofactor reconstitution leads to giant amphiphiles, which form vesicular aggregates in aqueous solution.