Depletion of mitochondrial DNA in the skeletal muscle of two cirrhotic patients with severe asthenia

Sequence and organization of the human mitochondrial genome

Stephen K. Anderson, Alan T. Bankier, B. G. Barrell et al. · Nature · 1981 · 9.7K citations

Medicine, Genetics, Molecular Genetics +12

Mitochondrial Genetics: A Paradigm for Aging and Degenerative Diseases?

Douglas C. Wallace · Science · 1992 · 1.3K citations

Life Sciences, Genetics, Molecular Genetics +17

Depletion of muscle mitochondrial DNA in AIDS patients with zidovudine-induced myopathy

E. Arnaudo, Sarah Shanske, S. DiMauro et al. · The Lancet · 1991 · 505 citations

Life Sciences, Infectious Diseases, Molecular Biology +17

Recombination via flanking direct repeats is a major cause of large-scale deletions of human mitochondrial DNA

Shuji Mita, Rosario Rizzuto, Carlos T. Moraes et al. · Nucleic Acids Research · 1990 · 343 citations · Full text

Life Sciences, Genetics, Neurology +15

Zidovudine-induced mitochondrial disorder with massive liver steatosis, myopathy, lactic acidosis, and mitochondrial DNA depletion

Patrick Chariot, Irène Drogou, I de Lacroix-Szmania et al. · Journal of Hepatology · 1999 · 259 citations

Medicine, Internal Medicine, Pathology +17