Behavioural profiles of two Wistar rat lines selectively bred for high or low anxiety-related behaviour

Validation of open : closed arm entries in an elevated plus-maze as a measure of anxiety in the rat

Sharon Pellow, Philippe Chopin, Sandra E. File et al. · Journal of Neuroscience Methods · 1985 · 5.8K citations

Social Sciences, Behavioral Sciences, Psychology +9

Depression: a new animal model sensitive to antidepressant treatments

Roger D. Porsolt, Manuel Pichon, M Jalfre · Nature · 1977 · 4.4K citations

Medicine, Neuroscience, Psychiatry +12

The open-field test: A critical review.

Roger Walsh, Robert A. Cummins · Psychological Bulletin · 1976 · 2.4K citations · Full text

Public Health, Behavioral Sciences, Experimental Design +7

Gene-targeting studies of mammalian behavior: is it the mutation or the background genotype?

Robert Gerlai · Trends in Neurosciences · 1996 · 885 citations

Life Sciences, Genetics, Molecular Biology +14

OPEN‐FIELD BEHAVIOR IN THE RAT: WHAT DOES IT MEAN?*

Victor H. Denenberg · Annals of the New York Academy of Sciences · 1969 · 581 citations

Life Sciences, Behavioral Sciences, Zoology +11