Concepedia

CYCLOSPORINE, FK506, MYCOPHENOLATE MOFETIL, AND PREDNISOLONE DIFFERENTIALLY MODULATE CYTOKINE GENE EXPRESSION IN HUMAN AIRWAY-DERIVED EPITHELIAL CELLS

Pieter Borger, H. F. Kauffman, J. A. B. Timmerman, Janny Scholma, J. W. K. van den Berg, G. H. Ko ter

Transplantation · 2000 · 34 citations · 22 references

DOI

Abstract

The data provide evidence that relevant concentrations of CsA and MMF in vivo may enhance the inflammatory processes in the lower airways of patients after lung transplantation.

References

22

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

Jun S. Liu, Jesse D. Farmer, Willam S. Lane et al. · Cell · 1991 · 4.1K citations

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Immunosuppression by Glucocorticoids: Inhibition of NF-κB Activity Through Induction of IκB Synthesis

Nathalie Auphan‐Anezin, Joseph A. DiDonato, Caridad Rosette et al. · Science · 1995 · 2.4K citations

Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

Neil A. Clipstone, Robert H. Crabtree · Nature · 1992 · 1.6K citations

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Cyclosporine induces cancer progression by a cell-autonomous mechanism

Minoru Hojo, Takashi Morimoto, Mary A. Maluccio et al. · Nature · 1999 · 1.1K citations

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FK-506- and CsA-sensitive activation of the interleukin-2 promoter by calcineurin

Stephen J. O’Keefe, Jun‐ichi Tamura, Randall L. Kincaid et al. · Nature · 1992 · 854 citations

, , +10