Antibiotic Resistance in Helicobacter pylori Strains and its Effect on<i>H. pylori</i>Eradication Rates in a Single Center in Korea

Abstract

We observed an increase in resistance to clarithromycin and an overall increase in multi-drug resistance during the 2 study periods. The effectiveness of the eradication regimen was low with combinations of clarithromycin and amoxicillin, particularly in the clarithromycin-resistant group. Thus, eradication of H. pylori depends upon periodic monitoring of antimicrobial susceptibility.