Concepedia

Sonogashira coupling in natural product synthesis

Dan Wang, Shuanhu Gao

Organic Chemistry Frontiers · 2014 · 207 citations · 70 references

DOI

Concepts

Abstract

This review will focus on selected applications of Sonogashira coupling and subsequent transformations as key steps in the total synthesis of natural products.

References

70

A convenient synthesis of acetylenes: catalytic substitutions of acetylenic hydrogen with bromoalkenes, iodoarenes and bromopyridines

Kenkichi Sonogashira, Yasuo Tohda, Nobue Hagihara · Tetrahedron Letters · 1975 · 5.1K citations

, , +11

The Atom Economy—A Search for Synthetic Efficiency

BM Trost · Science · 1991 · 4.7K citations

, , +16

The Palladium‐Catalyzed Cross‐Coupling Reactions of Organotin Reagents with Organic Electrophiles [New Synthetic Methods (58)]

J. K. Stille · Angewandte Chemie International Edition in English · 1986 · 3.4K citations

, , +9

Palladium‐Catalyzed Cross‐Coupling Reactions in Total Synthesis

K. C. Nicolaou, Paul G. Bulger, David Šarlah · Angewandte Chemie International Edition · 2005 · 2.7K citations

, , +6

Atom Economy—A Challenge for Organic Synthesis: Homogeneous Catalysis Leads the Way

Barry M. Trost · Angewandte Chemie International Edition in English · 1995 · 2.6K citations

, , +16