Publication | Closed Access
Total synthesis of porcine cholecystokinin-33 (CCK-33)
19
Citations
0
References
1987
Year
Medicinal ChemistryBioorganic ChemistryBiochemistryAmino AcidNatural SciencesPeptide LibraryPeptoidPeptide EngineeringMaximum Protection StrategyTotal SynthesisPeptide SynthesisProtein EngineeringPharmacologySulphated Tyrosyl ResidueNatural Product Synthesis
Porcine cholecystokinin-pancreozymin (CCK), which is a 33 amino acid peptide having a sulphated tyrosyl residue at position 27, was synthesized by the classical solution procedure applying our maximum protection strategy, for which the phenoxyacetyl group was used for the first time for protection of Ser residues.