Tilorone Hydrochloride: Human Toxicity and Interferon Stimulation

Abstract

Tilorone hydrochloride was studied in humans to determine whether it would be a safe and effective interferon inducer in man. Both systemic and topical application failed to produce detectible interferon, and toxicity was noted using both routes of administration. This study indicates that even in the high topical doses, tilorone HCl is neither safe nor effective.