Concepedia

Topical Toxicity Testing

Topical Toxicity Testing is a preclinical assessment method that evaluates the adverse effects of chemical substances on the skin following direct dermal application, distinguished from systemic toxicity testing by its focus on localized cutaneous responses.

479

Publications

20.3K

Citations

1.8K

Authors

554

Institutions

Publications per year

2017–2026

71

Variants

Dermal Toxicity Testing

Parents

Publications

479

METHODS FOR THE STUDY OF IRRITATION AND TOXICITY OF SUBSTANCES APPLIED TOPICALLY TO THE SKIN AND MUCOUS MEMBRANES

John H. Draize, Geoffrey E. Woodard, Herbert O. Calvery · Journal of Pharmacology and Experimental Therapeutics · 1944 · 2.6K citations

, , +8

The Effect of Topically Applied Compound F in Selected Dermatoses

Marion B. Sulzberger, Victor H. Witten · Journal of Investigative Dermatology · 1952 · 364 citations · Full text

, , +11

Systemic Uptake of Diethyl Phthalate, Dibutyl Phthalate, and Butyl Paraben Following Whole-Body Topical Application and Reproductive and Thyroid Hormone Levels in Humans

Nadeem Rezaq Janjua, Gerda Krogh Mortensen, Anna‐Maria Andersson et al. · Environmental Science & Technology · 2007 · 298 citations

, , +17

Urinary excretion of phthalates and paraben after repeated whole‐body topical application in humans

Nadeem Rezaq Janjua, Hanne Frederiksen, Niels E. Skakkebæk et al. · International Journal of Andrology · 2008 · 277 citations · Full text

, , +14

Cutaneous sodium lauryl sulphate irritation potential: age and regional variability

Klaus‐Peter Wilhelm, Howard I. Maïbach · British Journal of Dermatology · 1990 · 206 citations

, , +16

1–5 of 479

Authors

1.8K

  1. NA
    Nancy A. Monteiro‐Riviere

    North Carolina State University, United States

    8 publications · 206 citations

    8

    h-index

  2. SE
    Stacey E. Anderson

    National Institute for Occupational Safety and Health, United States

    7 publications · 301 citations

    7

    h-index

  3. HI
    Howard I. Maïbach

    University of California, San Francisco, United States

    6 publications · 413 citations

    6

    h-index

  4. EL
    Ewa Lukomska

    National Institute for Occupational Safety and Health, United States

    6 publications · 263 citations

    6

    h-index

  5. MS
    Monika Schäfer‐Korting

    Freie Universität Berlin, Germany

    5 publications · 177 citations

    5

    h-index

1–5 of 1.8K

Institutions

554

  1. University of California, San Francisco

    San Francisco, United States

    11 h-index

    26 publications

    1.3K citations

  2. Universidade de São Paulo

    São Paulo, Brazil

    11 h-index

    30 publications

    989 citations

  3. Procter & Gamble (United States)

    Cincinnati, United States

    10 h-index

    21 publications

    533 citations

  4. North Carolina State University

    Raleigh, United States

    9 h-index

    30 publications

    772 citations

  5. National Institute for Occupational Safety and Health

    Washington D.C., United States

    9 h-index

    49 publications

    1.9K citations

  6. University of Arizona

    Tucson, United States

    8 h-index

    38 publications

    1.3K citations

  7. National Institute of Health Sciences

    Tokyo, Japan

    7 h-index

    30 publications

    620 citations

  8. L'Oréal (France)

    Clichy, France

    6 h-index

    21 publications

    1.3K citations

1–8 of 554

Venues

  1. PubMed

    Repository · 38 publications · 962 citations

    21

    h-index

  2. Contact Dermatitis

    21 publications · 715 citations

    16

    h-index

  3. British Journal of Dermatology

    18 publications · 788 citations

    15

    h-index

  4. Toxicology and Applied Pharmacology

    TAAP · 13 publications · 606 citations

    13

    h-index

  5. Journal of the American College of Toxicology

    20 publications · 493 citations

    13

    h-index

1–5