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Publication | Open Access

Specific Variants in the MLH1 Gene Region May Drive DNA Methylation, Loss of Protein Expression, and MSI-H Colorectal Cancer

DOIFull Paper Access

43

Citations

40

References

2010

Year

Miralem Mrkonjic, Nicole M. Roslin, Celia M.T. Greenwood, Stavroula Raptis, Aaron Pollett, Peter W. Laird, Vaijayanti Pethe, Theodore Chiang, Darshana Daftary, Elizabeth Dicks,
PLoS ONE

Abstract

The observed association of rs1800734 with MSI-H CRC occurs through its effect on the MLH1 promoter methylation, MLH1 IHC deficiency, or both.

References

YearCitations

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