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Sustained localized expression of ligand for the activating NKG2D receptor impairs natural cytotoxicity in vivo and reduces tumor immunosurveillance

Nkg2d ReceptorNatural CytotoxicityNatural Killer CellsCancer ImmunosurveillanceImmunologyTumor ImmunityCell DeathImmunologic MechanismImmune Checkpoint InhibitorLocalized ExpressionImmunotherapyMedicineCell BiologyCell SignalingTumor MicroenvironmentTumor Biology