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The antiepidermal growth factor receptor monoclonal antibody cetuximab/C225 reduces hypoxia-inducible factor-1 alpha, leading to transcriptional inhibition of vascular endothelial growth factor expression

Hypoxia-inducible Factor-1 AlphaAngiogenesisMedicineImmunologyEndothelial DysfunctionTranscriptional InhibitionAutoimmunityVascular BiologyNeovascularizationVascular Endothelial Growth FactorImmunotherapyCell BiologyTumor Microenvironment