Concepts in Magnetic Resonance · 2002 · 28 citations · 34 references
EngineeringBioengineeringBiomedical EngineeringHeat TransferMicrowave EngineeringUltrasonographyMagnetic Resonance ImagingMagnetic Resonance Imaging PhysicsMedical ImagingMedical Imaging PhysicsUltrasound ImagingUltrasound PhysicsControl FeedbackHyperthermiaMagnetic ResonanceMagnetic Resonance PhysicsMicrowave HeatingMicrowave Heating MechanismsPhase ShiftsSpatial Temperature Variation
Abstract Microwave heating is a promising technique for hyperthermia treatment of tumors, but is not yet a standard clinical method. Problems include the inability to control automatically and noninvasively the temporal and spatial temperature behavior. Magnetic resonance imaging (MRI) can be used to map thermal changes via phase shifts in gradient‐echo images and has recently been incorporated into simple feedback systems for ultrasound heating. In this paper, we show the first demonstration of closed‐loop feedback control of microwave heating using MRI‐derived maps of both temperature and specific absorption rate as the inputs to a feedback algorithm. © 2002 Wiley Periodicals, Inc. Concepts in Magnetic Resonance (Magn Reson Engineering) 15: 101–110, 2002.
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Thermal effects of focused ultrasound on the brain: determination with MR imaging.
Kullervo Hynynen, Natalia Vykhodtseva, Alvin Chung et al. · Radiology · 1997 · 227 citations