Vaccination with Glutamic Acid Decarboxylase Plasmid DNA Protects Mice from Spontaneous Autoimmune Diabetes and B7/CD28 Costimulation Circumvents That Protection

Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes

Daniel L. Kaufman, Michael Clare‐Salzler, Jide Tian et al. · Nature · 1993 · 1.1K citations · Full text

Murine Insulin-dependent Diabetes, Biochemistry, Medicine +7

Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice

Roland Tisch, Xiaodong Yang, Steven M. Singer et al. · Nature · 1993 · 949 citations

Inflammation, Metabolic Syndrome, Acid Decarboxylase Correlates +10

B Lymphocytes Are Critical Antigen-Presenting Cells for the Initiation of T Cell-Mediated Autoimmune Diabetes in Nonobese Diabetic Mice

David Serreze, Sara Fleming, Harold D. Chapman et al. · The Journal of Immunology · 1998 · 454 citations

Immunological Memory, Immunogenetics, Autoimmune Disease +13

The Roles of Costimulation and Fas in T Cell Apoptosis and Peripheral Tolerance

Luk Van Parijs, Alexander Ibraghimov, Abul K. Abbas · Immunity · 1996 · 355 citations · Full text

Signal Transduction, Autoimmune Disease, T-regulatory Cell +14

Pancreatic expression of interleukin-4 abrogates insulitis and autoimmune diabetes in nonobese diabetic (NOD) mice.

Regula Mueller, Troy Krahl, Nora Sarvetnick · The Journal of Experimental Medicine · 1996 · 307 citations · Full text

T-regulatory Cell, Immunology, Immune Regulation +20