Differences in the Cellular Localization and Agonist-Mediated Internalization Properties of the α₁-Adrenoceptor Subtypes

Turning off the signal: desensitization of β‐adrenergic receptor function

William P. Hausdorff, Marc G. Caron, Robert J. Lefkowitz · The FASEB Journal · 1990 · 1.3K citations

Life Sciences, Biochemistry, Pharmacology +17

Differential Affinities of Visual Arrestin, βArrestin1, and βArrestin2 for G Protein-coupled Receptors Delineate Two Major Classes of Receptors

Robert H. Oakley, Stéphane A. Laporte, Jason A. Holt et al. · Journal of Biological Chemistry · 2000 · 882 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Phosphodiesterase activation by photoexcited rhodopsin is quenched when rhodopsin is phosphorylated and binds the intrinsic 48-kDa protein of rod outer segments.

Ursula Wilden, S W Hall, H. Kühn · Proceedings of the National Academy of Sciences · 1986 · 793 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Functional desensitization of the isolated beta-adrenergic receptor by the beta-adrenergic receptor kinase: potential role of an analog of the retinal protein arrestin (48-kDa protein).

Jeffrey Benovic, H. Kühn, Ingo Weyand et al. · Proceedings of the National Academy of Sciences · 1987 · 489 citations · Full text

Life Sciences, Biochemistry, Physiology +16

Structure and mechanism of the G protein-coupled receptor kinases.

James Inglese, Neil J. Freedman, Walter J. Koch et al. · Journal of Biological Chemistry · 1993 · 483 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12