Endoplasmic reticulum aminopeptidase 1 (ERAP1) exhibits functionally significant interaction with HLA-B27 and relates to subtype specificity in ankylosing spondylitis

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

Paul R. Burton, Martin D. Tobin, Kate Elliott et al. · Nature Genetics · 2007 · 1.4K citations · Full text

Life Sciences, Genetics, Molecular Genetics +14

Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility

David M. Evans, Chris C. A. Spencer, Jennifer J. Pointon et al. · Nature Genetics · 2011 · 907 citations · Full text

Life Sciences, Immunology, Molecular Biology +12

Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci

David M. Evans, Claire Farrar, David Harvey et al. · Nature Genetics · 2010 · 668 citations · Full text

Life Sciences, Genetics, Molecular Genetics +14

HLA–B27 misfolding and the unfolded protein response augment interleukin‐23 production and are associated with Th17 activation in transgenic rats

Monica DeLay, Matthew J. Turner, E. Klenk et al. · Arthritis & Rheumatism · 2009 · 391 citations · Full text

Life Sciences, Immunology, Pathology +17

The HLA-A,B "negative" mutant cell line C1R expresses a novel HLA-B35 allele, which also has a point mutation in the translation initiation codon

Jacqueline Zemmour, Ann‐Margaret Little, D. J. Schendel et al. · The Journal of Immunology · 1992 · 287 citations · Full text

Life Sciences, Genetics, Immunology +14