Obstructive Lung Diseases: Texture Classification for Differentiation at CT

Abstract

An automated technique for differentiation between a variety of obstructive lung diseases on the basis of textural analysis of thin-section computed tomographic (CT) images is described. From four regions of interest on each image, local texture information was extracted and represented by a 13-dimensional vector that contained statistical moments of the CT attenuation distribution, acquisition-length parameters, and co-occurrence descriptors. A supervised Bayesian classifier was used for texture feature segmentation. The technique was tested with a new cohort of subjects (n = 33, 660 regions of interest) with a similar spectrum of diseases. The proposed technique discriminates well between patterns of obstructive lung disease on the basis of parenchymal texture alone.