Flavopiridol increases therapeutic ratio of radiotherapy by preferentially enhancing tumor radioresponse

Blockage of the vascular endothelial growth factor stress response increases the antitumor effects of ionizing radiation.

David H. Gorski, Michael A. Beckett, Nora Jaskowiak et al. · PubMed · 1999 · 868 citations

Medicine, Oncology, Radiation Oncology +17

Microcolony Survival Assay for Cells of Mouse Intestinal Mucosa Exposed to Radiation

H. Rodney Withers, M. M. Elkind · International Journal of Radiation Biology and Related Studies in Physics Chemistry and Medicine · 1970 · 705 citations

Medicine, Cell Biology, Radiation Biophysics +16

Anti-epidermal growth factor receptor antibody C225 inhibits angiogenesis in human transitional cell carcinoma growing orthotopically in nude mice.

Paul Perrotte, Takayuki Matsumoto, Keiji Inoue et al. · PubMed · 1999 · 601 citations

Medicine, Oncology, Pharmacology +17

Induction of Vascular Endothelial Growth Factor by Hypoxia Is Modulated by a Phosphatidylinositol 3-Kinase/Akt Signaling Pathway in Ha-ras-Transformed Cells Through a Hypoxia Inducible Factor-1 Transcriptional Element

Nathalie M. Mazure, Eunice Y. Chen, Keith R. Laderoute et al. · Blood · 1997 · 509 citations · Full text

Life Sciences, Biochemistry, Cell Biology +16

In vivo enhancement of tumor radioresponse by C225 antiepidermal growth factor receptor antibody.

Luka Milas, Kathy A. Mason, Nancy Hunter et al. · PubMed · 2000 · 503 citations

Medicine, Oncology, Radiation Oncology +14