Chemical Composition and Topology of Poly(lactide‐<i>co</i>‐glycolide) Revealed by Pushing MALDI‐TOF MS to Its Limit

Abstract

Software developed in house in combination with a recently developed method of MALDI-TOF MS enable not only the elucidation of individual chain structures of poly(lactide-co-glycolide), a polymer used extensively in the medical sector, but a full characterization of this copolymer including even its chemical composition and topology (random, gradient, block (see figure), or alternating). Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2006/z600594_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.