Changes in adult <i>Nippostrongylus brasiliensis</i> during the development of immunity to this nematode in rats: 2. Total lipids and neutral lipids

Abstract

SUMMARY The total lipids and the amount of neutral lipids of male and female N. brasiliensis , from 7-day and 15-day infections, have been studied quantitatively. There is an increase in total lipids from 10·9 ± 2 to 15·5 ± 2 % in females and an increase from 8·4 ± 1 to 14·6 ± 2 % in males. In both sexes there is a rise in cholesterol and trigylceride content and a fall in free fatty acid content. These changes are discussed with reference to the development of immunity of the host to this nematode. I wish to thank Mrs B. Fisher, Mr A. W. Pearson and Mr N. Sykes for assistance during this work. These results form part of a programme of work supported by the A.R.C. while I was at the Molteno Institute, University of Cambridge, and continued at the Houghton Poultry Research Station. I wish to thank Dr P. Tate for accommodation at the Molteno Institute during the early part of this work.