A randomised double-blind placebo-controlled trial with <i>Lactobacillus acidophilus</i> La-5 and <i>Bifidobacterium animalis</i> subsp. <i>lactis</i> BB-12 for maintenance of remission in ulcerative colitis

Abstract

In this small randomised placebo-controlled trial no significant clinical benefit of Probio-Tec AB-25 could be demonstrated in comparison with placebo for maintaining remission in patients with left-sided ulcerative colitis. A difference may be achieved in larger studies, but the clinical significance of this would be questionable. This study was registered in ClinicalTrial.gov (NCT00268164).