Concepedia

The interferon‐regulated gene signature is elevated in subacute cutaneous lupus erythematosus and discoid lupus erythematosus and correlates with the cutaneous lupus area and severity index score

Inbal Braunstein, R Klein, Joyce Okawa, Victoria P. Werth

British Journal of Dermatology · 2012 · 173 citations · 13 references

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Abstract

Patients with SCLE and DLE have an IFN signature, as seen in SLE. The level of gene expression correlates with cutaneous disease activity. These findings support a shared pathogenesis between SLE and some subtypes of CLE.

References

13

Plasmacytoid Dendritic Cells (Natural Interferon- α/β-Producing Cells) Accumulate in Cutaneous Lupus Erythematosus Lesions

Lóránt Farkas, Klaus Beiske, Fridtjof Lund‐Johansen et al. · American Journal Of Pathology · 2001 · 721 citations · Full text

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The CLASI (Cutaneous Lupus Erythematosus Disease Area and Severity Index): An Outcome Instrument for Cutaneous Lupus Erythematosus

Joerg Albrecht, Lynne Taylor, Jesse A. Berlin et al. · Journal of Investigative Dermatology · 2005 · 487 citations · Full text

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Association of increased interferon‐inducible gene expression with disease activity and lupus nephritis in patients with systemic lupus erythematosus

Xuebing Feng, Hui Wu, Jennifer M. Grossman et al. · Arthritis & Rheumatism · 2006 · 476 citations

Heterozygous Mutations in TREX1 Cause Familial Chilblain Lupus and Dominant Aicardi-Goutières Syndrome

Gillian Rice, William G. Newman, John Dean et al. · The American Journal of Human Genetics · 2007 · 403 citations · Full text

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An Interferon Signature in the Peripheral Blood of Dermatomyositis Patients is Associated with Disease Activity

Emily C. Baechler, Jason W. Bauer, Catherine A. Slattery et al. · Molecular Medicine · 2007 · 300 citations · Full text

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