Tumor antigen-specific T helper cells in cancer immunity and immunotherapy

Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity.

Glen Dranoff, Elizabeth M. Jaffee, A Lazenby et al. · Proceedings of the National Academy of Sciences · 1993 · 2.8K citations

Medicine, Immunology, Oncology +17

Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1

Jerry H. Brown, Theodore S. Jardetzky, Joan C. Gorga et al. · Nature · 1993 · 2.4K citations

Life Sciences, Immunology, Molecular Biology +12

Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide

Lawrence J. Stern, Jerry H. Brown, Theodore S. Jardetzky et al. · Nature · 1994 · 1.6K citations

Life Sciences, Biochemistry, Immunology +17

The Central Role of CD4+ T Cells in the Antitumor Immune Response

Kenneth E. Hung, Robert J. Hayashi, Anne Lafond-Walker et al. · The Journal of Experimental Medicine · 1998 · 1.3K citations · Full text

Life Sciences, Immunology, Oncology +17

Specificity and promiscuity among naturally processed peptides bound to HLA-DR alleles.

Roman M. Chicz, Robert G. Urban, Joan C. Gorga et al. · The Journal of Experimental Medicine · 1993 · 885 citations · Full text

Life Sciences, Immunology, Molecular Biology +17