Concepedia

A Longitudinal Study of Plasma and Urinary Cortisol in Pregnancy and Postpartum

Caroline Jung, Jui T. Ho, David J. Torpy, Anne Rogers, Matthew Doogue, John G. Lewis, Raymond Czajko, Warrick J. Inder

The Journal of Clinical Endocrinology & Metabolism · 2011 · 376 citations · 36 references

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Abstract

Our study demonstrated elevations in total plasma cortisol and CBG concentrations during pregnancy and with low-dose OCP use. Pregnancy was also associated with significant increases in plasma free cortisol and UFC, suggesting that the rise in total plasma cortisol is contributed to by up-regulation of the maternal hypothalamic-pituitary-adrenal axis in addition to elevated CBG.

References

36

A placental clock controlling the length of human pregnancy

Mark McLean, Andrew Bisits, Joanne Davies et al. · Nature Medicine · 1995 · 915 citations

, , +11

Glucocorticoid stimulates expression of corticotropin-releasing hormone gene in human placenta.

Bruce G. Robinson, Rodica L. Emanuel, David M. Frim et al. · Proceedings of the National Academy of Sciences · 1988 · 443 citations · Full text

, , +20

Maternal plasma adrenocorticotropin and cortisol relationships throughout human pregnancy

Bruce R. Carr, C. Richard Parker, James D. Madden et al. · American Journal of Obstetrics and Gynecology · 1981 · 368 citations

, , +7

Evidence for local stimulation of ACTH secretion by corticotropin-releasing factor in human placenta

Felice Petraglia, Paul E. Sawchenko, Jean Rivier et al. · Nature · 1987 · 340 citations

, , +12

Immunoreactive Corticotropin-Releasing Hormone in Human Plasma During Pregnancy, Labor, and Delivery*

Atsushi Sasaki, Osamu Shinkawa, Andrew N. Margioris et al. · The Journal of Clinical Endocrinology & Metabolism · 1987 · 269 citations