Analysis of gene expression data using BRB-ArrayTools.

TLDR

BRB-ArrayTools is an integrated software system for comprehensive analysis of DNA microarray experiments, developed by professional biostatisticians and incorporating methods from leading statistical laboratories. The software is intended for biomedical scientists to access state‑of‑the‑art statistical methods for gene‑expression data analysis and to receive training in high‑dimensional data analysis. It provides extensive links to genomic websites for gene annotation and pathway analysis, hosts an archive of over 100 published microarray datasets with clinical data, and automatically imports data from the NCBI Gene Expression Omnibus. The software offers the most extensive set of tools for predictive classifier development and complete cross‑validation.

Abstract

BRB-ArrayTools is an integrated software system for the comprehensive analysis of DNA microarray experiments. It was developed by professional biostatisticians experienced in the design and analysis of DNA microarray studies and incorporates methods developed by leading statistical laboratories. The software is designed for use by biomedical scientists who wish to have access to state-of-the-art statistical methods for the analysis of gene expression data and to receive training in the statistical analysis of high dimensional data. The software provides the most extensive set of tools available for predictive classifier development and complete cross-validation. It offers extensive links to genomic websites for gene annotation and analysis tools for pathway analysis. An archive of over 100 datasets of published microarray data with associated clinical data is provided and BRB-ArrayTools automatically imports data from the Gene Expression Omnibus public archive at the National Center for Biotechnology Information.