Reduced Numbers of Blood Natural Regulatory T Cells in Stable Liver Transplant Recipients With High Levels of Calcineurin Inhibitors

The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

Craig L. Bennett, Jacinda R. Christie, Fred Ramsdell et al. · Nature Genetics · 2001 · 3.4K citations

Life Sciences, Genetics, Immunology +13

Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

Mary E. Brunkow, Eric W. Jeffery, Kathryn A. Hjerrild et al. · Nature Genetics · 2001 · 2.6K citations

Medicine, Molecular Biology, Pathology +3

X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy

Robert S. Wildin, Fred Ramsdell, Jane Peake et al. · Nature Genetics · 2001 · 1.9K citations

Medicine, Endocrinology, Pediatrics +17

Calcineurin Inhibitors, but not Rapamycin, Reduce Percentages of CD4+CD25+FOXP3+ Regulatory T Cells in Renal Transplant Recipients

David San Segundo, Juan Carlos Ruiz, María Jesús Izquierdo et al. · Transplantation · 2006 · 247 citations

Life Sciences, Immunology, Nephrology +17

Low circulating regulatory T-cell levels after acute rejection in liver transplantation

Ahmet Demirkıran, Alice Kok, Jaap Kwekkeboom et al. · Liver Transplantation · 2006 · 145 citations · Full text

Life Sciences, Immunology, Pathology +17