Iodohydrin Synthesis from Simple and Functionalised Olefins on Treatment with Periodic Acid and Sodium Bisulfite

Abstract

Abstract Periodic acid (H5IO6) in combination with sodium bisulfite was found to be a prominent reagent to convert simple and functionalised olefins into the corresponding iodohydrins in fair to good yields under mild conditions. Allylic alcohols gave iodohydrins whose orientation obeyed anti-Markovnikov rule in contrast to olefins which gave Markovnikov products.