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Transgene expression levels and kinetics determine risk of humoral immune response modeled in factor IX knockout and missense mutant mice

InflammationImmunogeneticsAllergyAutoimmune DiseaseMissense Mutant MiceHumoral ResponseImmune RegulationImmunologyImmunologic MechanismAutoimmunityHumoral ImmunityFactor Ix KnockoutImmune MediatorMedicineTransgene Expression LevelsImmune Dysregulation