Clinical Infectious Diseases · 2003 · 112 citations · 9 references
Life SciencesHematologyImmunologyClinical ImmunologyImmunotherapyMonoclonal AntibodiesB Cell ActivationB Cell BiologyB-cell ResponsesHumoral ImmunityImmune-related Adverse EventsMonoclonal Antibody TherapyAnti-cd20 Antibody TherapyAnti-cd20 TherapyB Cell-mediated ImmunityB-cell DisordersImmune-mediated ThrombocytopeniaPediatric Immune ThrombocytopeniaRelapsed Diffuse Large B-cell LymphomaRituximab-based Therapy
Treatment with the chimeric anti-CD20 monoclonal antibody rituximab induces rapid and long-lasting depletion of circulating B cells. We report the occurrence of enteroviral meningoencephalitis following rituximab therapy in 1 child with immune thrombocytopenia and in 1 adult patient with relapsed B cell lymphoma.
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