Concepedia

Metabolism of N-[4-hydroxyphenyl]retinamide (4-HPR) to N-[4-methoxyphenyl]retinamide (4-MPR) may serve as a biomarker for its efficacy against human breast cancer and melanoma cells

European Journal of Cancer · 1998 · 22 citations · 23 references

Concepts

BiochemistryMedicineHuman Breast CancerMetabolic RemodelingAnti-cancer AgentDrug DevelopmentMetabolomicsPharmacologyMelanoma CellsDrug Discovery

References

23

The retinoids—Biology, chemistry and medicine

The Journal of Steroid Biochemistry and Molecular Biology · 1996 · 1.2K citations

Medicine, Retina, Retinal Biology +1

N-(4-Hydroxyphenyl)retinamide, a new retinoid for prevention of breast cancer in the rat.

Richard C. Moon, Henry J. Thompson, Peter J. Becci et al. · PubMed · 1979 · 385 citations

Ocular Disease, Retina, Ophthalmology +15

Chemoprevention of cancer with retinoids

Gary L. Peck · Gynecologic Oncology · 1981 · 368 citations

Chemoprevention Strategy, Medicine, Photocarcinogenesis +3

N-(4-hydroxyphenyl)retinamide induces apoptosis of malignant hemopoietic cell lines including those unresponsive to retinoic acid.

Domenico Delia, Antonella Aiello, Luciano Lombardi et al. · PubMed · 1993 · 248 citations

Chemoprevention Strategy, Retinamide Induces Apoptosis, Retinoic Acid Receptor +18

4-Hydroxyphenyl Retinamide Is a Highly Selective Activator of Retinoid Receptors

Andrea Fanjul, Domenico Delia, Marco A. Pierotti et al. · Journal of Biological Chemistry · 1996 · 183 citations · Full text