Concepedia

Solvent-free synthesis of functionalized 5-imino-2,5-dihydrofurans from isocyanides, activated acetylenes and alkyl cyanoformates

Issa Yavari, Tayebeh Sanaeishoar, Leila Azad

Mendeleev Communications · 2011 · 18 citations · 11 references

DOI

Concepts

Abstract

The reaction between alkyl(aryl) isocyanides, dialkyl acetylenedicarboxylates and alkyl cyanoformates under solvent-free conditions leads to dialkyl 2-cyano-5-alkyl(aryl)imino-2-alkoxy-2,5-dihydrofuran-3,4-dicarboxylates in high yields.

References

11

Reactions of isocyanides with activated acetylenes in protic solvents

Thomas R. Oakes, Daniel J. Donovan · The Journal of Organic Chemistry · 1973 · 59 citations

, , +4

Small ring systems from isocyanides. I. Reaction of isocyanides with hexafluorobutyne-2

Thomas R. Oakes, Howard G. David, Frederick J. Nagel · Journal of the American Chemical Society · 1969 · 58 citations

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Three-component reactions involving zwitterionic intermediates for the construction of heterocyclic systems: one pot synthesis of highly functionalized γ-iminolactones

Abbas Ali Esmaeili, Hamid Zendegani · Tetrahedron · 2005 · 45 citations

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Efficient synthesis of functionalized 2,5-dihydrofurans and 1,5-dihydro-2H-pyrrol-2-ones by reaction of isocyanides with activated acetylenes in the presence of hexachloroacetone

Issa Yavari, Maryam Sabbaghan, Zinatossadat Hossaini · Monatshefte für Chemie - Chemical Monthly · 2008 · 44 citations

, , +8

A mild and efficient method for the synthesis of 2,5-dihydro-5-imino-2-methylfuran-3,4-dicarboxylates via an isocyanide-based multicomponent reaction

Ahmad Shaabani, Ali Hossein Rezayan, Sabrieh Ghasemi et al. · Tetrahedron Letters · 2009 · 37 citations

, , +4