Journal of Clinical Microbiology · 2001 · 35 citations · 14 references
Life SciencesInfectious DiseasesMicrobiologyBacteriologyMedical MicrobiologyNeuroinfectious DiseasesBacterial InfectionsCentral Nervous System InfectionsCentral Nervous System Infection TreatmentGentamicin TherapyMeningitis Antibiotic TherapyNeurologic InfectionsPortosystemic ShuntsShunt InfectionSurgical ManipulationVentriculoperitoneal Shunt Surgery
A 66-year-old man with four indwelling ventriculoperitoneal shunts for multiloculated hydrocephalus from a complicated case of meningitis a year before developed shunt infection based on a syndrome of fever, drowsiness, and cerebrospinal fluid neutrophil pleocytosis in the background of repeated surgical manipulation to relieve successive shunt blockages. The cerebrospinal fluid culture, which yielded a motile Enterococcus species, was believed to originate from the gut. This isolate was lost in storage and could not be characterized further. The patient improved with vancomycin and high-dose ampicillin therapy. He relapsed a month later with Enterococcus gallinarum shunt infection, which responded to high-dose ampicillin and gentamicin therapy. This is probably the first case report of motile Enterococcus infection of the central nervous system.
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